1. Manage Tabs
Ctrl+T  | Open a new tab  | 
Ctrl+Shift+T  | Reopen the last tab closed (up to 10 tabs)  | 
Ctrl+W/ Ctrl+F4  | Close the tab  | 
Ctrl+1 through Ctrl+8  | Switch to the first tab, the second, etc.  | 
Ctrl+9  | Switch to the last tab  | 
Ctrl+Tab/Ctrl+Page Up  | Switch to the next tab  | 
Ctrl+Shift+Tab/Ctrl+Page Down  | Switch to the previous tab  | 
Ctrl+N  | Open a new window  | 
Ctrl+Shift+N  | Open a new incognito window  | 
Ctrl+Shift+W/ Alt+F4  | Close the current window  | 
Ctrl+left-click  | Open the link in a new background tab  | 
Ctrl+Shift+left-click  | Open the link in a new foreground tab  | 
Shift+left-click  | Open the link in a new window  | 
Alt+left-click  | Download the link  | 
Ctrl + click on "Search Google for" from a drop down menu  | Open Google search in a new background tab  | 
Shift + click on "Search Google for" from a drop down menu  | Open Google search in a new window  | 
Drag link to an existing tab  | Open the link in the selected tab  | 
Drag link to tab bar  | Open the link in a new tab in the specified position on the tab strip  | 
Hold Ctrl + click on tabs in the tab bar  | Select multiple tabs (to rearrange them or create a new window)  | 
Hold Shift + click on two tabs in the tab bar  | Select all the tabs between two tabs (to rearrange them or create a new window)  | 
Ctrl+L/ Alt+D  | Set focus to the address bar (highlights the current webpage URL if available)  | 
Shift+Alt+T  | Set focus to the toolbar  | 
Ctrl+E/ Ctrl+K  | Enter search query in the address bar  | 
Arrow Down to highlight, then Shift + Delete  | Remove a prediction from the address bar  | 
Type search term and press Enter  | Perform a search using the search engine associated with the keyword or the URI  | 
Type and press Alt+Enter  | Open the site or a search in a new foreground tab  | 
Type and press Win+Enter  | Open the site or a search in a new background tab (doesn't work in Windows 10)  | 
Type and press Alt+Shift+Enter  | Open the site or a search in a new background tab (works in Windows 10)  | 
Type and press Shift+Enter  | Open the site or a search in a new window  | 
Type and press Ctrl+Enter  | Add www. to beginning and .com to end of input and open the web address in the current tab  | 
Type and press Ctrl+Alt+Enter  | Add www. to beginning and .com to end of input and open the web address in a new foreground tab  | 
Type and press Ctrl+Win+Enter  | Add www. to beginning and .com to end of input and open the web address in a new background tab (doesn't work in Windows 10)  | 
Type and press Ctrl+Shift+Enter  | Add www. to beginning and .com to end of input and open the web address in a new window  | 
Type name of search engine and press Tab  | Tab-to-Search feature. E.g. Typing in 'yahoo.com' plus tab opens yahoo search. Add/edit search engines via 'Under the Hood' -> Basic -> Search Engines.  | 
F6  | Alternate focus between address bar, bookmarks bar and webpage  | 
Arrow Down/Arrow Up  | Scroll down / scroll up  | 
Page Down/Page Up  | Scroll one page down / up  | 
Space/Shift+Space  | Scroll one page down / up  | 
Home/End  | Jump to beginning / to end of webpage  | 
Ctrl+[+]/-  | Zoom in / zoom out (or Ctrl+mousewheel)  | 
Ctrl+0 (zero)  | Return zoom to normal text size  | 
Ctrl+U  | View webpage source  | 
F11  | Turn full screen on / off  | 
F  | Turn fullscreen on / off for some video types (e.g. YouTube)  | 
M  | Mute / unmute some video types (e.g. YouTube)  | 
Alt+Home  | Jump to homepage  | 
Alt+Arrow Left/Arrow Right  | Jump to previous webpage visited / jump to next webpage  | 
F5/Ctrl+R  | Reload current webpage  | 
Ctrl+F5/Shift+F5  | Reload current webpage with cache override  | 
Esc  | Stop webpage loading  | 
Tab/Shift+Tab with focus on webpage  | Jump to next / previous link  | 
Enter on link  | Open link in current tab  | 
Ctrl+Enter on link  | Open link in a new background tab  | 
Shift+Ctrl+Enter on link  | Open link in a new foreground tab  | 
Shift+Enter on link  | Open link in a new window  | 
Alt+Enter on link  | Download link  | 
Shift+F10  | Open context menu (simulate right mouse button)  | 
Ctrl+A  | Select all content on webpage  | 
Ctrl+C with content selected  | Copy selected content to clipboard  | 
Ctrl+P  | Print current webpage (Chrome Print Dialog)  | 
Ctrl+Shift+P  | Print current webpage (Native Windows Print Dialog)  | 
Ctrl+O  | Open file  | 
Ctrl+S  | Save current webpage  | 
Alt+F  | Open Wrench Menu (I'd call it file menu to remember the shortcut)  | 
Ctrl+H  | Open History tab  | 
Ctrl+J  | Open Downloads tab  | 
Shift+Esc  | View Google Task manager  | 
F1  | Chrome Help  | 
Ctrl+Shift+Del  | Open the Clear Browsing Data options  | 
Ctrl+F/F3  | Find text on webpage. Press Enter for.  | 
Enter/Shift+Enter with text found on webpage  | Find next / find previous match  | 
Ctrl+G/Ctrl+Shift+G with text found on webpage  | Find next / find previous match  | 
Esc  | With focus on Search box: Close Search box  | 
Ctrl+Shift+B  | Show or hide bookmarks bar  | 
Ctrl+Shift+O  | Open Bookmark Manager  | 
Ctrl+D  | Add bookmark for current webpage  | 
Ctrl+Shift+D  | Saves all open pages as bookmarks in a new folder  | 
Drag URL to bookmark bar  | Bookmark webpage (can be URL from address bar or link from page)  | 
Alt+F, then B  | Open Bookmark Manager Tab  | 
9.1 Accessing DevTools and DevTools Basics
Ctrl+Shift+I (or F12)  | Open Developer Tools  | 
Ctrl+Shift+J  | Open Developer Tools (With Focus on Javascript Console)  | 
Ctrl+Shift+C  | Toggle Element Inspection mode  | 
Ctrl+Shift+C (2x)  | Switch Focus on Developer Tools (there is not really a shortcut for focusing on the Developer Tool, but this is a workaround. Watch the Inspector Mode Icon change color as you press for guidence. Finally, this works only if DevTools are docked; if they are not, simpy switch between windows with Alt+Tab)  | 
?  | Show General Settings Dialog (press Esc to exit)  | 
Ctrl+[/]  | Switch to next / Switch to previous panel (add Alt to the combination to reverse the direction)  | 
Ctrl+D  | Dock / Undock Developer Tool  | 
Ctrl+Shift+M  | Toggle (mobile) Device Mode  | 
Ctrl+F  | Search Text in Source  | 
Ctrl+Shift+F  | Search Text across sources  | 
Ctrl+O  | Search by Filename  | 
Ctrl+[+]/-  | Zoom in / Zoom out Developer tools  | 
Ctrl+0 (zero)  | Zoom to default  | 
9.2 Elements Panel
Ctrl+Arrow Up  | Focus on the Elements content (this is strangely nowhere documented, but worked for me; without this one, you cannot use any of the other shortcuts below without clicking on the content first)  | 
Arrow Up/Arrow Down  | Navigate upwards/ downwards  | 
Ctrl+Z/Ctrl+Y  | Undo / Redo Change  | 
Arrow Right/Arrow Left  | Expand / Collapse  | 
Left-click on arrow  | Expand node  | 
Ctrl+Alt+Left-click  | Expand/collapse node with all children  | 
Enter  | Edit the element  | 
H  | Hide the element  | 
F2  | Toggle edit as HTML  | 
9.3 Styles Panel
Left-click  | Edit Rule  | 
Left-click on white space  | Insert new property  | 
Ctrl+Left-click on property  | Go to line of style rule property declaration  | 
Shift+Left-click on property  | Cycle through the color definition value  | 
Tab/Shift+Tab  | Edit next / edit previous property  | 
Arrow Up/Arrow Down  | Increase / decrease value by 1  | 
Page Up/Page Down  | Increase / decrease value by 10  | 
Shift+Page Up/Page Down  | Increase / decrease value by 100  | 
Alt+Arrow Up/Arrow Down  | Increase / decrease value by 100  | 
9.4 Sources Panel
F8, Ctrl+\  | Pause / resume script execution  | 
F8, Ctrl+\  | Pause / resume script execution  | 
F10, Ctrl+'  | Step over next function call  | 
F11, Ctrl+;  | Step into next function call  | 
Shift+F11, Ctrl+Shift+;  | Step out of current function  | 
Ctrl+./,  | Select next / select previous call frame  | 
Left-click on line-number  | Toggle breakpoint condition  | 
Right-click on line number  | Edit breakpoint condition  | 
Alt+Delete  | Delete individual words  | 
Ctrl+/  | Comment a line or selected text  | 
Ctrl+S  | Save changes to local modifications  | 
Ctrl+Alt+S  | Save all changes  | 
Ctrl+G  | Go to line  | 
Ctrl+O  | Search by filename  | 
Ctrl+P+number  | Jump to line number  | 
Ctrl+O+number +number  | Jump to column  | 
Ctrl+Shift+O  | Go to member  | 
Alt+W  | Close active tab  | 
Ctrl+Enter  | Run snippet  | 
9.5 Code Editor
Ctrl+M  | Go to matching bracket  | 
Ctrl+P+number  | Jump to line number  | 
Ctrl+O+number +number  | Jump to column  | 
Ctrl+/  | Toggle comment  | 
Ctrl+D  | Select next occurrence  | 
Ctrl+U  | Undo last selection  | 
9.6 Timeline Panel
Ctrl+E  | Start / stop recording  | 
Ctrl+S  | Save timeline data  | 
Ctrl+O  | Open / Load timeline data  | 
9.7 Profiles Panel
Ctrl+E  | Start / stop recording  | 
9.8 Console Panel
Arrow Right  | Accept Suggestion  | 
Arrow Up/Arrow Down  | Previous / next command (line)  | 
Ctrl+`  | Focus the Console  | 
Ctrl+L  | Clear Console  | 
Shift+Enter  | Multi-line entry  | 
Enter  | Execute  | 
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